As we celebrate Women’s History Month, it’s pertinent to remember that the health and well-being of young ladies is crucial for their future success and happiness. In recent years, one area that has received a lot of attention is the endocannabinoid system and the use of marijuana among young adults, particularly young women. As a psychiatrist, I have seen firsthand the negative impact that marijuana can have on mental health, especially in young women.

The endocannabinoid system is a complex network of receptors, molecules, and enzymes that regulate various physiological processes, including mood, appetite, pain, and immune function. This system is involved in the effects of cannabis on the brain and body. THC, the main psychoactive component in marijuana, binds to the endocannabinoid receptors in the brain, leading to the characteristic “high” associated with cannabis use.

While marijuana is legal in some states, it’s essential to understand that it can have serious adverse effects on young adults, particularly young women. Research has shown that women are more vulnerable to the harmful effects of marijuana than men. Several scientific papers show that women are more likely to develop anxiety, depression, and other mental health issues after using cannabis compared to men. This is likely because women have a higher concentration of endocannabinoid receptors in their brains than men, making them more sensitive to the effects of THC.

Moreover, research has shown that the use of marijuana during adolescence and young adulthood can have long-term negative effects on brain development, especially in areas of the brain responsible for memory, attention, and decision-making. This is particularly concerning for young women, as these cognitive functions are crucial for academic and professional success.

It’s also important to note that marijuana use can adversely affect reproductive health. Studies have shown that cannabis use can disrupt the menstrual cycle and reduce fertility in women. Additionally, marijuana use during pregnancy has been associated with low birth weight and developmental problems in infants.

As a psychiatrist, I strongly advise young women to avoid using marijuana, particularly during adolescence and young adulthood. It’s important to remember that marijuana use can negatively affect mental health, brain development, and reproductive health. Many effective treatments are available to help individuals overcome marijuana addiction and improve their overall health and well-being. If you or someone you know is struggling with marijuana use, seeking professional help is vital.


Olukayode O. Awosika, MD, FAPA.