When other treatments haven’t been enough there are more options.
Spravato (esketamine) is an FDA-approved nasal spray for adults whose depression hasn’t improved with other medications. It’s given in our clinic, with a provider monitoring you throughout every treatment session.
A different kind of depression treatment
Spravato is a prescription nasal spray containing esketamine. It works differently from traditional antidepressants and is approved for adults with treatment-resistant depression, and for adults with major depression who are having thoughts or behaviors of suicide. It is used together with an oral antidepressant or as directed by your provider.
Because of how it works, Spravato is only available through a certified treatment setting. You take each dose in our clinic under supervision and stay for monitoring afterward. It is not a take-home medication.
Depression that hasn’t responded to treatment isn’t a failure of willpower. It’s a signal that a different approach may be worth exploring.
Who Spravato may help
Spravato is not right for everyone. A psychiatric evaluation is the only way to know whether it fits your situation.
Spravato may be worth discussing if…
Tell your provider first if…
These factors don’t always rule Spravato out, but they affect safety and must be reviewed before treatment.
What to expect, from first call to treatment
Treatment starts with an evaluation, then moves to scheduled in-clinic sessions. Your care team explains each step before it happens.
Psychiatric Evaluation
Your provider reviews your symptoms, treatment history, current medications, and medical conditions to confirm Spravato is appropriate. If it is, we begin the benefits check and any prior authorization your plan requires.
Treatment Session (about 2+ hours)
You check in, have your blood pressure taken, and self-administer the nasal spray with staff nearby. You are then monitored for at least two hours. Some people feel drowsy, dizzy, or disconnected for a while, which is expected and temporary.
Going Home Safely
Before leaving, your provider confirms you’re ready. You must not drive or operate machinery until the next day after a full night’s restful sleep, so please arrange a ride home.
Ongoing Schedule & Follow-Up
Sessions are typically more frequent at the start (often twice weekly for the first month) and then taper to weekly or every other week as your provider recommends. Your progress is reviewed regularly.
How to prepare for a treatment day
A little preparation helps your session go smoothly. Your care team will confirm the details before your first visit.
Know your coverage before you begin
Spravato coverage varies by plan. Many insurers cover it when specific criteria are met and usually require prior authorization. We handle the verification so you aren’t left guessing.
Coverage is not guaranteed and depends on your plan and clinical eligibility. Call us and we’ll explain your options if Spravato isn’t covered.
We verify your benefits
Share your insurance details and our team checks your Spravato coverage, copay, and deductible.
We manage prior authorization
If your plan requires approval, we prepare and submit the clinical documentation for you.
You know the cost up front
We walk you through what to expect before your first treatment session is scheduled.
“Finding the right treatment takes patience, and you don’t have to do it alone.”
We take the time to understand your history, explain every step, and adjust your plan as you progress.
Answers before you book
Spravato acts on a different brain pathway than traditional antidepressants and is taken as a nasal spray in a supervised setting. Your provider can explain how it fits with the medications you take now.
Plan on at least two hours. That covers check-in, the dose, and the required monitoring period afterward. Your provider will tell you when it’s safe to leave.
The most common are dizziness, nausea, drowsiness, a feeling of disconnection, and a temporary rise in blood pressure. These usually fade within hours, which is why you are monitored in clinic.
No. You need someone else to take you home, and you shouldn’t drive or operate machinery until the next day after a full night’s restful sleep.
Many plans cover it when criteria are met, often with prior authorization. We verify your benefits and manage the paperwork before you start.
Responses vary. Some people notice changes within the first few weeks, and your provider will review your progress with you regularly to decide how to continue.
This page is for general information and is not medical advice. Spravato (esketamine) has important safety information, including risks of sedation, dissociation, breathing difficulty, misuse, and suicidal thoughts. Ask your provider for the full Prescribing Information and Medication Guide.
Ready to talk about your options?
Reach out and our team will help you take the first step. A consultation is simply a conversation about whether Spravato may be right for you.